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Kadimastem, an Israeli biotech company, has aloft $5.15 actor in a clandestine placement. The investors included Altshuler Shaham Advance House.

PRESS RELEASE

NESS ZIONA, Israel, October 2, 2018 /PRNewswire/ –Israeli biotechnology aggregation Kadimastem (TASE: KDST) appear today the achievement of an advance annular of $5.15 million, by way of clandestine placement, at a allotment bulk of 65 agorot.

Participants in the annular accommodate the Altshuler Shaham Advance House ($2.5 million), which is thereby accretion its backing in the aggregation to about 20%, as able-bodied as the company’s authoritative shareholders, Prof. Michel and Claire Revel ($500K) and Julien Ruggieri ($600K), as able-bodied as aggregation stakeholders (Mr. Yigal Fatran, affiliate of the BOD of the company; Dr. Michal Izrael, VP R&D for ALS and Neurodegenerative Diseases; Dr. Arik Hasson, VP R&D; and Mr. Yehuda Feinberg, CFO) and added clandestine investors ($1.55 million).

The bulk aloft is planned to be acceptable to accredit the aggregation to ability artefact ability after-effects from cohorts A and B in the Phase I/IIa analytic balloon in ALS patients; these after-effects are actual significant. The aggregation expects to ability this anniversary aural the advancing year and a quarter.

The Phase I/IIa analytic balloon is actuality conducted by the Department of Neurology of the Hadassah Ein Karem Medical Center, accepted to accommodate 21 participants. The cold of the balloon is to appraise the assurance and ability of the company’s product, AstroRx®, in patients.

Until all-encompassing the anniversary of accepting ability after-effects from cohorts A and B, the aggregation will not accession new disinterestedness financing, except for the afterward cases: Costs from a pharma or biotech aggregation with a bazaar cap of at atomic $100M, or aural the framework of co-funding of the aggregation will accept a admission from the California Institute of Adorning Medicine (co-funding claim of 20%), at a allotment bulk college than the allotment bulk of the accepted costs round. In the accident that the aggregation raises new disinterestedness not beneath the aloft terms, the backing of the investors from the accepted annular will be preserved. That said, by a accommodation of a majority of the investors in this annular this action can be waived.

Yossi Ben Yossef, CEO of Kadimastem, noted, “I am blessed that we’ve completed this cogent raise, led by Altshuler Shaham and aggregation authoritative shareholders Prof. Michel and Claire Revel and Julien Ruggieri. Stopping or slowing bottomward the ache progression in cohorts A and B in the in the Phase I/IIa analytic balloon in ALS patients will represent an ability on a all-around scale.”

About KadimastemKadimastem Ltd. (http://www.Kadimastem.com) is a analytic date biotechnology aggregation developing automated adorning therapies based on animal beginning axis beef (hESC) for the analysis of neurodegenerative diseases such as ALS, as able-bodied as diabetes. The aggregation was founded in 2009 by Prof. Michel Revel and Yossi Ben Yosef and is listed on the Tel Aviv Stock Exchange (TASE: KDST). The company’s administrator is Dr. Eli Opper, aforetime the Chief Scientist of Israel’s Ministry of Industry, Trade, and Labor, and the company’s Accurate Advising Lath consists of arch scientists and antecedents in their fields. The company’s investors, in accession to its founders, accommodate Altshuler Shaham Advance House, adopted investors (Julien Ruggieri and Avi Meizler) and added institutional investors.

Kadimastem was founded on the base of patent-protected technologies developed in Prof. Michel Revel’s class at the Weizmann Institute of Science. Based on the company’s different abstruse platform, Kadimastem develops adorning therapies to adjustment and alter tissues and organs by application action beef differentiated from axis cells. The aggregation focuses on clearing advantageous academician beef to abutment the survivability of damaged assumption beef as corpuscle analysis for ALS and clearing insulin-producing pancreatic corpuscle for the analysis of insulin-dependent diabetes.

Kadimastem has an all-encompassing accurate advising board, featuring arresting scientists and pioneers: In the beginning axis corpuscle acreage – Assistant Joseph Itskovitz-Eldor, a apple acclaimed able and avant-garde in pluripotent axis corpuscle analysis and above arch of Obstetrics and Gynecology at Rambam Medical Center, serves both as a administrator and a chief cardinal adviser in the company, and Prof. Benjamin Reubinoff, Administrator of the Hadassah Animal Beginning Axis Corpuscle Analysis Center and Chief Physician at the Department of Obstetrics and Gynecology at the Hadassah University Medical Center; in the neurodegenerative ache acreage – Prof. Tamir Ben Hur, Arch of the Department of Neurology and Division of Medical Neurosciences at Hadassah Medical Center in Jerusalem; and in the diabetes field, Prof. Shimon Efrat, assistant of Animal Molecular Genetics and Juvenile Diabetes at Tel Aviv University and a apple acclaimed able in corpuscle backup analysis for diabetes, and Prof. Eddy Karnieli, above Administrator of the Institute for Endocrinology, Diabetes and Metaism at the Rambam Medical Center and a apple acclaimed able in these fields.

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